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Treatment interruptions news

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Adherence
Treatment breaks set for a come-back?

Two and half years after a major study of HIV treatment interruption was halted because of a higher risk of death in people who stopped

Published
12 November 2008
By
Gus Cairns
Side-effects
Continued antiretroviral therapy reduces bone mineral density in SMART study

A sub-study of the SMART trial has found greater losses of bone mineral density in people who stayed on continuous antiretroviral therapy, compared to those

Published
27 October 2008
By
Derek Thaczuk
HIV treatment
BHIVA: Many patients and clinicians still need educating about the benefits of treatment

Both HIV-positive individuals and their clinicians require further education around the benefits of earlier initiation of therapy, and better understanding of the risks of treatment

Published
08 May 2008
By
Edwin J. Bernard
Resistance
Planned interruption of highly active antiretroviral therapy does not select drug resistance mutations in HIV-1-infected children

Stopping highly active antiretroviral therapy (HAART) containing two non-nucleoside reverse transcriptase inhibitors (NNRTI) for 9 or 14 days in HIV-1-infected children with viral suppression did

Published
07 May 2008
By
Tom Egwang
Treatment interruptions
SMART study reaffirms that HIV replication is harmful, even at CD4 counts above 350

Uncontrolled HIV replication is associated with a higher risk of serious illness and death even when the CD4 cell count is above the currently recommended

Published
14 April 2008
By
Tom Egwang
Treatment interruptions
Benefit of starting HIV treatment early outweighs the risk of toxicities, SMART study shows

Starting antiretroviral therapy at a CD4 cell count above 350 - the current threshold for starting treatment - reduced the risk of serious illness and

Published
14 April 2008
By
Tom Egwang
Treatment interruptions
CROI: Biomarker changes may help explain detrimental effects of treatment interruption

Several biomarkers associated with inflammation, blood coagulation, or endothelial dysfunction are significantly elevated during treatment interruption and may partially explain the increased risk of cardiovascular

Published
07 February 2008
By
Liz Highleyman
Treatment interruptions
CROI: Risk of treatment interruption persists after restarting HAART

The detrimental effects of interrupting antiretroviral therapy are reduced, but not entirely reversed, after restarting treatment, researchers with the SMART study reported on Monday at

Published
05 February 2008
By
Liz Highleyman
Side-effects
High prevalence of asymptomatic heart disease in HIV-positive patients

Asymptomatic ischaemic heart disease is common in HIV-positive individuals, according to a subanalysis of the SMART treatment interruption study published in the January 11th edition

Published
09 January 2008
By
Michael Carter
Adherence
Up to 40% of ART recipients in Africa have died or discontinued treatment within two years

Up to 40% of all patients receiving anti-HIV drugs in sub-Saharan Africa are thought to have either died or discontinued treatment within two years, according

Published
17 October 2007
By
Edwin J. Bernard
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